Division of Neurology: City-Wide Neurology Grand Rounds
City-Wide Neurology Grand Rounds
Alberto J. Espay, MD, MSc, FAAN
Professor of Neurology
Director and Endowed Chair
James J. and Joan A. Gardner Center for Parkinson’s Disease and Movement Disorders
University of Cincinnati
Title: Revisiting Models of Neurodegenerative Diseases for the Era of Precision Medicine
- To review the pitfalls in the clinico-pathologic model of neurodegenerative diseases.
- To compare the current phenotype-anchored biomarker development model with biomarker-driven molecular disease subtyping for future application of precision medicine in PD.
- To consider a conceptual shift in research efforts from clinico-pathologic convergence to systems biology divergence.